News
Apr 24, 2024: Endothelial cells are sensitive to low shear in just a short time! Mohanish's paper about endothelial sensing of temporary low-shear stress has been published in AJP-Heart. Check it out.
Apr 18, 2024: Our microscope is re-assembled at the new HSTEM Building!
Mar 27, 2024: Our collaborative work with Steve McGowan at Iowa was published in American Journal of Respiratory Cell and Molecular Biology. Good job, Mohanish!
Feb 29, 2024: We are in the new building! Good job everyone helping smooth transition to HSTEM Complex!
Jan 15, 2024: Nik's paper regarding myosin-independent ECM stiffness sensing has been published in Communications Materials, a Nature Portfolio Journal. Congrats!
Dec 17, 2023: Dr. Han was awarded with Wallace Research Foundation grant for the study of collagen type V's role in wound healing in vivo and in vitro.
March 3, 2023: Dr. Han was awarded with NIH R15 grant for linking mechanotransmission to mechanosignaling.
Dec 22, 2022: Dr. Han was awarded with Wallace Research Foundation grant for the study of collagen type V's role in mechanotransduction.
June 22, 2022: Sam and Sue's algorithm that rescues tracking of a large, local deformation happening in TFM has been published in PLOS One! Check it out.
April 25, 2022: Shaina's minireview paper about mechanobiology in Ehlers-Danlos Syndrome has been published in Frontiers in Cell and Developmental Biology. Check it out!
April 7, 2022: Kathleen received Outstanding Undergraduate Scholar award. Congrats!
April 1, 2022: Mohanish was awarded 3rd place in GRC poster competition. Congrats!
December 6, 2021: Dr. Han was awarded with MTU's Research Excellence Fund! We appreciate HRI and ICC's support as well as ones by the BME department and the College of Engineering.
October 2021: Dr. Han attended BMES and chaired in a session called 'Cancer Systems Biology'. Mohanish also served in the MTU booth. Got inspired by many mechanobiology works.
September 2021: Nikhil's paper on the TFM protocol has been published in Current Protocols! Check this out.
September 2021: Mohanish's book chapter on micropillars and microcontact printing has been published in Methods in Vascular Tissue Engineering book edited by Feng and Tony.
July 6, 2021: Nikhil received an HRI graduate fellowship of $3000 for the Fall 2021 semester! Congrats! TechToday Coverage
Apr 30, 2021: Shaina completed her undergraduate study and graduated. She will continue to work with us as a graduate student. Congratulations and welcome again!
Apr 29, 2021: Shaina received an Outstanding Undergraduate Researcher Award, presented to an undergraduate student who has significant research accomplishments, including presentations at conferences or co-authorship of publications. Great job, Shaina!
Apr 29, 2021: Katie received a Michael R. Neuman Award, presented to an undergraduate student (sophomore-senior status) who has made contributions in research! Great job, Katie!
Mar 29, 2021: Dr. Han's research on nascent adhesion and contribution of talin-vinculin pre-association is finally published in eLife!
Dec 19, 2020: Sarah Rowe, a first-year BME undergrad, has joined the lab. Welcome, Sarah!
May 19, 2020: Sam Haarman, a BME-ME double-majoring undergrad, has joined the lab since October 2019, and now his info is up in the People section. Welcome, Sam!
April 20, 2020: Sam and Katie have received URIP fellowship for 2020-2021 academic year. Congrats!
March 20, 2020: Undergraduate student, Katie Heusser, has joined the lab since this January, and now her info is up in People section. Welcome, Katie!
March 16, 2020: Shaina and Sam's proposals to SURF were accepted! Shaina will investigate collagen V's effect on cell adhesion and Sam will implement efficient 3D TFM algorithm.
Jan 29, 2020: Claudia's paper about cancer detection was just published in Heliyon. Please see how computer vision helps detect sub-population of different expression of receptor marker!
Jan 10, 2020: Dr. Han has joined the Institute of Computing and Cybersystems as a member of the Center for Data Sciences in the College of Computing research institute.
Dec 4, 2020: Dr. Han has been affiliated in Mechanical Engineering at MTU as an Affiliated Assistant Professor.
Sep 20, 2019: Dr. Han was awarded with AREA grant (1R15GM135806-01) from NIH NIGMS with the title “Nascent Adhesion-Based Mechano-Transmission for Extracellular Matrix Stiffness Sensing”. This award will give confidence boost for our stiffness sensing project.
Sep 19, 2019: Three undergraduate students, Karl Schneider, Sam Haarman and Nate Broetsman join the lab. Welcome to the lab!
Aug 10, 2019: Our paper, titled "Formation of talin-vinculin pre-complexes dictates maturation of nascent adhesions by accelerated force transmission and vinculin recruitment" has been published as a pre-print at BioRxiv.
Aug 1, 2019: Our paper, titled "Direct Arp2/3-vinculin binding is essential for cell spreading, but only on compliant substrates and in 3D" has been published as a pre-print at BioRxiv.
July 25 2019: Dr. Han has given an invited talk at Hongik University via an invitation from Prof. Suhyung Choi (Chemical Engineering, HU).
July 24, 2019: Dr. Han has given a talk at Myongji University via an invitation from Prof. Dohyun Kim (Mechanical Engineering, Myongji University).
July 18, 2019: Dr. Han has given a talk at Inha Medical School via an invitation from Prof. Sugeon Yang (Biological Science, Inha university).
July 15, 2019: Dr. Han has given a talk at Yonsei School of Dentistry via an invitation from Prof. Jeongheon Cha (School of Dentistry, Yonsei University).
July 8, 2019: Dr. Han has given an invited talk at KAIST via an invitation from Prof. Jessie Jeon (Mechanical Engineering, KAIST).
May 18, 2019: Dr. Han has received the best poster award from the 6th Zoo meeting: Check the news out from this twitter.
Abbee's paper "Enhanced Dendritic Actin Network Formation in Extended Lamellipodia Drives Proliferation in Growth-Challenged Rac1P29S Melanoma Cells" was published in Developmental Cell, 49, 444-460.e449. Our TFM and adhesion analysis were used in the paper. Please check it out how mechanosensitive signaling melanoma cells use to gain drug resistance here!
May 18 2018: Dr. Han has received the best poster award from the 6th Zoo meeting: Check the news out from this twitter.
Abbee's paper "Enhanced Dendritic Actin Network Formation in Extended Lamellipodia Drives Proliferation in Growth-Challenged Rac1P29S Melanoma Cells" was published in Developmental Cell, 49, 444-460.e449. Our TFM and adhesion analysis were used in the paper. Please check it out how mechanosensitive signaling melanoma cells use to gain drug resistance here!
October 9 2018: Job submission pipeline to Superior HPC was successfully established. Now all the analyses will become much faster.
September 2018: The total internal reflection fluorescence microscopy (TIRF) was successfully implemented in Great Lake Research Center!
September 2018: Han Lab's research was highlighted in the BME department news. Check it out!
August 2018: Mehdi Abtahi has joined the Mechanobiology Lab as a Ph.D. student. He will expand our TFM package to three dimension and make the tool more accurate and reliable. Welcome Mehdi!
May 2018: Mohanish Chandurkar has joined the lab as a master student. He will develop a shear flow system on TFM substrate. Welcome, Mohanish!
L1 rocks! More people in mechanobiology community is giving appreciation of our pioneering L1-TFM for its accuracy and better force resolution. Check out recent citations on Dr. Han's Nature Method paper.
April 5, 2018: Shaina Royer and Sue Kim has received an Undergraduate Research Internship Program award, starting from fall 2018. Welcome Sue!
Jan 2, 2018: Nikhil Mittal has joined Han group as the very first, Ph.D. student. He will investigate the nascent adhesion based mechanosensing in ChoK cells. Welcome Nik!
Nov 10, 2017: Dr. Sangyoon Han was invited as a speaker at Chemistry Department Seminar Series at Tech
Oct 20, 2017: Dr. Sangyoon Han gave an invited talk at Chicago Cytoskeleton Meeting, Northwestern University in Chicago.
Aug 21, 2017: Dr. Sangyoon Han has joined Michigan Tech, Biomedical Engineering.
